Gene interactions and pathways from curated databases and text-mining

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EFNA1 — MAPK3

Text-mined interactions from Literome

Cheng et al., J Biol Chem 2001 : Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK dependent but nuclear factor-kappa B-independent mechanism
Tang et al., J Nutr Biochem 2007 (Neoplasms...) : Furthermore, EGCG inhibited the ephrin-A1 mediated phosphorylation of EphA2 and ERK-1/2
Nie et al., Nat Neurosci 2010 : We also found that EphA receptor activation by ephrin-A ligands in neurons led to inhibition of extracellular signal regulated kinase 1/2 ( ERK1/2 ) activity and decreased inhibition of Tsc2 by ERK1/2
Fritsche-Guenther et al., Histopathology 2010 (Bone Neoplasms...) : Further in vitro investigations on the functional role of EphA2 and EFNA1 showed that EFNA1 ligand binding induced increased tyrosine phosphorylation, receptor degradation and downstream mitogen activated protein kinase ( MAPK ) activation
Bi et al., J Neurophysiol 2011 : Conversely, BDNF had no effect on subsequently applied ephrin-A5-Fc or EphA5-Fc. Consistent with this, ephrin-A5-Fc also prevented BDNF induced activation of p42/44 MAPK