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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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EGR1 — SOD3

Text-mined interactions from Literome

Maehara et al., FASEB J 2001 : Forced expression of Egr-1 in the cells activated Mn-SOD transcription in a dose dependent manner
Bek et al., J Immunol 2003 : Overexpression of EGR-1 induces down-regulation of copper-zinc superoxide dismutase and manganese superoxide dismutase and stimulates the generation of reactive oxygen species ( ROS ) via the NADH/NADPH-oxidase system
Nozik-Grayck et al., Am J Physiol Lung Cell Mol Physiol 2008 (Anoxia...) : Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling ... EC-SOD overexpression also prevented the early hypoxia dependent upregulation of the redox-sensitive transcription factor Egr-1 and the procoagulant protein TF
Hartney et al., PloS one 2011 (Anoxia...) : We now hypothesize that loss of EC-SOD in chronically hypoxic calves leads to extracellular superoxide mediated upregulation of Egr-1
Minc et al., J Biol Chem 1999 : The human copper-zinc superoxide dismutase gene ( SOD1 ) proximal promoter is regulated by Sp1, Egr-1 , and WT1 via non-canonical binding sites