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EPHB2 — ERVK-6

Text-mined interactions from Literome

Kumar et al., Am J Physiol Cell Physiol 2007 (Calcium Signaling) : It has been previously shown that beta-arrestins are required for signal termination, internalization, and ERK1/2 activation downstream of protease-activated-receptor-2 (PAR-2) , but it is unclear whether they are functionally redundant or mediate specific events
Bhavaraju et al., Eur J Pharmacol 2008 : In order to determine whether OXSI-2 inhibited Src family kinase mediated platelet responses, we evaluated its effect on Src family kinase (SFK) mediated signaling events in platelets, viz. Lyn mediated phosphorylation of Y352 on Syk, LAT-Y191 phosphorylation by Syk, and protease activated receptor (PAR) mediated phosphorylation of ERK
Kontos et al., Cancer Lett 2013 (Adenocarcinoma...) : KLK4 is an endogenous activator of protease activated receptor 1 (PAR1) in HT-29 colorectal adenocarcinoma cells, inducing PAR1 signaling and subsequent ERK1/2 activation