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EXO1 — PRKDC

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 40 proteins (association, anti bait coimmunoprecipitation) Wang et al., Cell 2006

Text-mined interactions from Literome

Karmakar et al., J Biol Chem 2002 (Werner Syndrome) : We find that although DNA-PKcs alone does not affect the WRN exonuclease activity, the additional presence of Ku mediates a marked inhibition of it ... The inhibition of WRN exonuclease by DNA-PKcs requires the kinase activity of DNA-PKcs
Kusumoto-Matsuo et al., Aging 2010 (Werner Syndrome) : The results show that DNA-PKcs selectively stimulates WRN helicase but not WRN exonuclease in vitro, affecting that WRN helicase unwinds and promotes the release of the full-length invading strand of a telomere D-loop model substrate