◀ Back to FGF2

F11R — FGF2

Pathways - manually collected, often from reviews:

• NCI Pathway Database Integrins in angiogenesis: JAM-A (F11R) → FGF2 (FGF2) (modification, activates) Naik et al., Blood 2003, Eliceiri et al., J Cell Biol 1998
  Evidence: mutant phenotype, assay, other species
• NCI Pathway Database Integrins in angiogenesis: alphav/beta3 Integrin/JAM-A complex (F11R-ITGAV-ITGB3) → FGF2 (FGF2) (modification, collaborate) Naik et al., Blood 2003
  Evidence: mutant phenotype, assay

Text-mined interactions from Literome

Hou et al., Ann Rheum Dis 2010 (Scleroderma, Diffuse) : Decreased expression of JAM-A on SSc ECs may result in a reduced response to proangiogenic basic fibroblast growth factor
Naik et al., Cell Adh Migr 2008 (Neoplasms) : We have previously shown that in endothelial cells, JAM-A regulates basic fibroblast growth factor , ( FGF-2 ) -induced angiogenesis via augmenting endothelial cell migration ... We have previously shown that in endothelial cells, JAM-A regulates basic fibroblast growth factor , ( FGF-2 ) -induced angiogenesis via augmenting endothelial cell migration
Peddibhotla et al., Mol Biol Cell 2013 : Our findings indicate that CD9 incorporates monomeric JAM-A into a complex with avß3 integrin, which responds to bFGF stimulation by JAM-A release to regulate mitogen activated protein kinase ( MAPK ) activation, endothelial cell migration, and angiogenesis