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FAS — IL15

Text-mined interactions from Literome

Chang et al., Yonsei Med J 2000 (HIV Infections) : The results were as follows : 1 ) IL-15 reduced culture induced lymphocyte apoptosis in HIV patients in a dose dependent manner, and reached a plateau level at a concentration of 100 ng/ml ; 2 ) IL-15 significantly reduced the level of apoptosis after 3 days ( 14 % ) and 5 days ( 15 % ) of culture in HIV patients, while no difference was observed in HIV ( - ) donors ; 3 ) The percentage of viable cells among the total number of lymphocytes was significantly enhanced by 25 % in HIV patients with IL-15 ; 4 ) Bcl-2 expression was decreased in HIV patients ( 53.9 +/- 12.3 % ) compared to HIV ( - ) donors ( 93.0 +/- 3.7 % ), and IL-15 increased Bcl-2 expression by 21.2 +/- 5.2 % in HIV patients ; 5 ) Fas expression was increased in HIV patients ( 70.2 +/- 4.6 % ) compared to HIV ( - ) donors ( 32.4 +/- 4.3 % ), and IL-15 increased Fas expression by 8.4 +/- 1.2 % in HIV ( - ) donors
Lin et al., Biol Neonate 2004 : CD95 expression ( both percent expression and MFI ) on CB CD4+/CD45RA+ cells were also enhanced by IL-15 , but to a lesser extent compared to the response of ABP
Yamada et al., Diabetologia 1996 (Autoimmune Diseases...) : Mouse islet cell lysis mediated by interleukin-1 induced Fas