Barkalow et al., Am J Physiol Cell Physiol 2003
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Activation of the small GTPases Rac and Cdc42 follows Fc gamma RIIA cross linking
Nilsson et al., Eur J Immunol 2005
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Inhibition of CD11b/CD18, but not of CD32 , the major neutrophil signaling Fc receptor, prevented Streptococcus induced NADPH oxidase dependent respiratory burst, and blocking of C3b/iC3b formation inhibited Streptococcus induced activation of Cdc42 , a small GTPase critically involved in transmitting pro-inflammatory signals to the cytoskeleton