Gene interactions and pathways from curated databases and text-mining

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CDKN1A — FOXG1

Text-mined interactions from Literome

Arden et al., Mol Cell 2004 (Cell Transformation, Neoplastic) : FoxG1 , a protein from a distinct Fox subfamily, binds FoxO/Smad complexes and blocks p21Cip1 expression
Adesina et al., J Neurooncol 2007 (Brain Neoplasms...) : Current reports indicate that FOXG1 represses TGF-beta induced expression of p21cip1 and cytostasis, and forms a transcriptional repressor complex with Notch signaling induced hes1
Chan et al., Br J Cancer 2009 (Ovarian Neoplasms) : The effect of FOXG1 on p21 ( WAF1/CIP1 ) transcriptional activity was examined by luciferase reporter assays ... Functionally, enforced expression of FOXG1 selectively blocked the TGF-beta induced p21 ( WAF1/CIP1 ) expressions and increased cell proliferation in ovarian cancer cells