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CD28 — GAB2

Text-mined interactions from Literome

Vandenberghe et al., J Exp Med 1992 : These results suggest that specific tyrosine phosphorylation, particularly of pp100 , occurs directly as a result of CD28 ligand binding and is involved in transducing the signal delivered through CD28 by accessory cells that express the B7/BB1 receptor
Parry et al., J Immunol 2006 : In this study, we show that ligation of CD28 by its natural ligand B7-1/CD80, induces tyrosine phosphorylation of Gab2 and its coassociation with Src homology phosphatase (SHP)-2 and class IA PI3K in Jurkat cells
Skålhegg et al., Scand J Immunol 1994 : The fact that pp100 phosphorylation in response to TCR/CD3-, CD28- and PMA stimulation and cAMP mediated inhibition are identical to the effects of the same stimuli on T-cell proliferation, makes this protein an interesting candidate in downstream signalling from these receptors