Gene interactions and pathways from curated databases and text-mining

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GCLC — TNF

Text-mined interactions from Literome

Haddad et al., Int Immunopharmacol 2002 (Translocation, Genetic) : Inhibition of gamma-glutamylcysteine synthetase , the rate limiting enzyme in the biosynthesis of GSH, by the action of L-buthionine- ( S, R ) -sulfoximine ( BSO ), potentiated LPS induced IL-1beta, IL-6 and TNF-alpha production
Yang et al., Biochem J 2005 : TNFalpha induces the expression and recombinant promoter activities of GCLC , GCLM and GSS in H4IIE cells