Gene interactions and pathways from curated databases and text-mining

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GH1 — TCF12

Text-mined interactions from Literome

Ezzat et al., Mol Endocrinol 2005 : The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility
Arellanes-Robledo et al., Anticancer Drugs 2010 (Liver Neoplasms, Experimental) : A search for the upstream mediator of these genetic alterations found that carcinogenesis inactivated by 87 % the signal transducer and activator of transcription 5 ( Stat5 ), a transcription factor that is activated by growth hormone signaling, but celecoxib treatment restored its activation
Heltemes-Harris et al., Ann N Y Acad Sci 2011 : The transcription factor signal transducer and activator of transcription 5 ( STAT5 ) is activated by a number of cytokine and growth hormone receptors and plays a key role in the development and function of many organ systems
Sharp et al., Bioessays 1990 : The transcription of rat prolactin and growth hormone genes in vitro requires a pituitary transcription factor , specific to certain cell types in the pituitary, which currently appears to be the PUF-I/Pit-1/GHF-1 protein
Campbell et al., J Biol Chem 1995 : Activation of acute phase response factor ( APRF ) /Stat3 transcription factor by growth hormone
Chang et al., J Biol Chem 1996 : The rat growth hormone promoter is synergistically activated by the pituitary-specific transcription factor , Pit-1, and the thyroid hormone receptor ( TR )