Gene interactions and pathways from curated databases and text-mining

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HDAC2 — MMP1

Text-mined interactions from Literome

Liu et al., Cancer Res 2003 (Lung Neoplasms...) : In this study, we test the possibility that HDAC inhibitor may increase RECK expression to inhibit MMP activation and cancer cell invasion
Wang et al., J Cereb Blood Flow Metab 2011 (Brain Edema...) : Our findings suggest that BBB protection by VPA involves HDAC inhibition mediated suppression of NF-?B activation, MMP-9 induction, and tight junction degradation