Shen et al., J Biol Chem 2005
:
In osteoblastic cells, Hes-1 , a downstream factor of the Notch signaling pathway, was found to enhance basal and 1,25 ( OH ) ( 2 ) D ( 3 ) -induced OPN transcription
Matsue et al., Bone 1997
(Bone Neoplasms...) :
Overexpression of HES-1 suppressed the vitamin D-dependent upregulation of osteopontin gene expression in these cells