Gene interactions and pathways from curated databases and text-mining

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CSF3 — HNRNPF

Text-mined interactions from Literome

Gasparetto et al., Cytokine 2002 (Breast Neoplasms) : The FL+G-CSF and FL+GM-CSF mobilized DCs were immature by morphologic and phenotypic criteria but stimulated allogeneic T-cells at levels similar to DCs generated in culture from PBMCs. Overnight culture ? of the immature DCs obtained from patients receiving either FL+G-CSF or FL+GM-CSF in TNF-alpha ? resulted in the generation of mature DCs
Bharadwaj et al., Cancer Res 2007 (Pancreatic Neoplasms) : IL-6 was able to suppress DC differentiation and G-CSF mainly acted on the suppressing allostimulatory capacity of DCs
Morris et al., Nat Med 2009 (Graft vs Host Disease) : Stimulation of host DCs by G-CSF subsequently unleashed a cascade of events characterized by donor natural killer T cell ( NKT cell ) activation, interferon-gamma secretion and CD40 dependent amplification of donor cytotoxic T lymphocyte function during the effector phase of GVHD
Layseca-Espinosa et al., J Immunol 2013 (Diabetes Mellitus, Type 1) : This is an indirect effect because adoptive transfer of G-CSF induced tolerogenic dendritic cells (DCs) promotes Treg accumulation