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CSF3 — HNRNPF
Text-mined interactions from Literome
Gasparetto et al., Cytokine 2002
(Breast Neoplasms) :
The
FL+G-CSF and FL+GM-CSF mobilized DCs were immature by morphologic and phenotypic criteria but stimulated allogeneic T-cells at levels similar to DCs generated in culture from PBMCs. Overnight culture ? of the immature DCs obtained from patients receiving either FL+G-CSF or FL+GM-CSF in TNF-alpha ?
resulted in the generation of mature
DCs
Bharadwaj et al., Cancer Res 2007
(Pancreatic Neoplasms) :
IL-6 was able to suppress DC differentiation and
G-CSF mainly
acted on the suppressing allostimulatory capacity of
DCs
Morris et al., Nat Med 2009
(Graft vs Host Disease) :
Stimulation of host
DCs by
G-CSF subsequently unleashed a cascade of events characterized by donor natural killer T cell ( NKT cell ) activation, interferon-gamma secretion and CD40 dependent amplification of donor cytotoxic T lymphocyte function during the effector phase of GVHD
Layseca-Espinosa et al., J Immunol 2013
(Diabetes Mellitus, Type 1) :
This is an indirect effect because adoptive transfer of
G-CSF induced tolerogenic
dendritic cells (DCs) promotes Treg accumulation