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ICOS — PI3

Text-mined interactions from Literome

Feito et al., Eur J Immunol 2003 (MAP Kinase Signaling System) : The association of phosphoinositide 3-kinase (PI-3K) to H4/ICOS was enhanced by H4/ICOS cross linking, and PI-3K inhibitors inhibited ERK and JNK activation and IL-4/IL-10 secretion, but not p38 MAP kinase or ZAP-70 activation
Nukada et al., Int Immunol 2006 : AILIM/ICOS signaling induces the activation of phosphoinositide-3 (PI3)-kinase , the product of which, phosphatidylinositol 3,4,5-trisphosphate ( PIP3 ), was found to be localized in the lamellipodia at the front part of the cells