Trembleau et al., J Immunol 2000
(Diabetes Mellitus, Type 1) :
In addition, IFN-gamma production in response to IA-2 and IDDM acceleration could be induced by IL-12 administration to 12-day-old NOD mice
Nicoletti et al., Endocrinology 1997
(Diabetes Mellitus, Type 1) :
Taken together, these results provide further in vivo evidence for the central pathogenic role of IFN gamma in BB rat IDDM and anticipate the usefulness of specific IFN gamma inhibitors in the prevention of the disease in the clinical setting