Gene interactions and pathways from curated databases and text-mining

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HGF — IFI27

Text-mined interactions from Literome

Tsubari et al., Mol Cell Biol 1999 : Though HGF did not differentially regulate the total levels of p27 in TGF-beta treated cells, p27 immunodepletion experiments suggested that upon treatment with both growth factors, less p27 is associated with Cdk2-cyclin E complexes, in parallel with restoration of the active form of Cdk2 and the associated kinase activity
Leshem et al., J Cell Physiol 2002 : Accordingly, this mutant reversed the inhibitory effects of HGF on the expression of the cyclin dependent kinase (CDK) inhibitor p27 and myogenic differentiation markers
Yang et al., J Cell Physiol 2007 (Carcinoma, Hepatocellular...) : At HD, HGF increased the mRNA levels of p21 and p27 , while lowering the levels of MAT genes, cyclin A, and c-met