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IFNB1 — TGFB1
Text-mined interactions from Literome
Ossege et al., Int Immunopharmacol 2001
(Multiple Sclerosis) :
The present data suggest that
IFN beta-1b induces the mRNA expression of
TGF beta-1 and TGF beta-R-II by PBMC, decreases that of TNF alpha and increases levels of sVCAM-1 and of circulating activated CD8 cells ( CD8CD38 ) in blood
Tanabe et al., Immunology 2007
(Disease Progression...) :
Furthermore,
IFN-beta reduced the expressions of
transforming growth factor-beta , basic fibroblast growth factor, collagen type I A2 and tissue inhibitor of metalloproteinase 1 messenger RNAs, which are related to the progression of liver fibrosis
Créange et al., BioDrugs 2000
:
IFNbeta increases anti-inflammatory T cell functions and the production of anti-inflammatory cytokines, such as
TGFbeta1
Zhang et al., Clin Neurol Neurosurg 2010
(Autoimmune Diseases...) :
IFNbeta inhibited IL-1beta, IL-23 and
transforming growth factor ( TGF ) -beta ( which induce Th17 cell differentiation ), and induced IL-27, IL-12p35 and IL-10 ( which suppress it ) in dendritic cells (DCs) and B-cells
Arnason et al., Clin Immunol Immunopathol 1996
(Autoimmune Diseases...) :
Production of the suppressive cytokines IL-10 and
transforming growth factor beta-1 is
increased in vitro by
IFNbeta1b
Arnason et al., J Neural Transm Suppl 1997
(Demyelinating Diseases...) :
In contrast ; production of
transforming growth factor beta-1 ( TGF beta 1 ) is
increased by
IFN beta-1b
Ossege et al., J Neuroimmunol 1998
(Multiple Sclerosis) :
The present data suggest that
IFNbeta-1b induces the expression of
TGFbeta-1- and TGFbeta-R-II-mRNA by PBMC and increases levels of sVCAM-1 and of circulating activated CD8 cells ( CD8CD38 ) in serum