Gaertner et al., J Control Release 2005
:
The mechanism by which ARC-encapsulation increased IFN-gamma activity in vivo remains uncertain
Withyachumnarnkul et al., Int J Biochem 1991
:
10. The results indicate that the IFN-gamma induced NAT suppression requires the integrity of the sympathetic nerve terminals and the IFN-gamma induced enhancement of melatonin production is accomplished through its direct action on pinealocytes
Withyachumnarnkul et al., J Pineal Res 1990
:
IFN-gamma had no effect on either NAT or HIOMT activities in the pineal glands
Walter et al., Immunopharmacol Immunotoxicol 1996
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Both IFN gamma and SLO activated NAT to 120 % ( P < 0.05 ) and 135 % ( P < 0.05 ), respectively ... The results suggested that not only the toxin of gram positive streptococcal bacteria SLO, but also the cytokine IFN gamma can stimulate NAT activity in rat hepatic cytosol ... While the enhancing SLO effect on NAT could not be neutralized by the inhibitor of transcription actinomycin D, NAT stimulation by IFN gamma was abolished by actinomycin D and by the inhibitor of translation, cycloheximide