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IL10 — LGALS1
Text-mined interactions from Literome
Cedeno-Laurent et al., J Immunol 2010
(Dermatitis, Contact) :
Moreover, in human skin-resident T cell cultures,
Gal-1hFc diminished IL-17 ( + ) T cells and increased IL-4 ( + ) and
IL-10 ( + ) T cells
Cedeno-Laurent et al., J Immunol 2012
(Dermatitis, Allergic Contact...) :
IL-10 synthesis was
stimulated by direct
Gal-1 engagement to cell surface glycoproteins, principally CD45, on activated Th cells and enhanced by IL-21 expression through the c-Maf/aryl hydrocarbon receptor pathway, independent of APCs ...
Gal-1 induced
IL-10 ( + ) T cells efficiently suppressed T cell proliferation and T cell mediated inflammation and promoted the establishment of cancer immune privileged sites