◀ Back to CXCL10
CXCL10 — IL17D
Text-mined interactions from Literome
Shimizu et al., J Immunol 2006
(Lung Neoplasms...) :
Finally, augmented mRNA expression of
IP-10 and monokine induced by IFN-gamma was detected at the s.c. B16F10 + IL-27 tumor site, and antitumor activity of
IL-27 was partially
inhibited by the administration of anti-IP-10
Shibata et al., J Invest Dermatol 2010
(Psoriasis) :
Furthermore,
IL-27 alone greatly
induced in vitro CXCL9,
CXCL10 , and CXCL11 production and tyrosine phosphorylation of signal transducer and activator of transcription 1 in normal human keratinocytes, while it suppressed the tumor necrosis factor-alpha induced production of IL-1alpha and CCL20
Cao et al., Chest 2012
(Pulmonary Disease, Chronic Obstructive...) :
IL-27 is elevated in patients with COPD and patients with pulmonary TB and
induces human bronchial epithelial cells to produce
CXCL10 ... The production of IL-27 is related to the pathogenesis of COPD and PTB, and
IL-27 induces the expression of
CXCL10 in bronchial epithelial cells through the activation of the PI3K-Akt signaling pathway
Zeitvogel et al., J Biol Chem 2012
(Chronic Disease...) :
Overexpression of SOCS3 in keratinocytes significantly diminished this enhanced
CXCL10 production in
response to
IL-27