Gene interactions and pathways from curated databases and text-mining

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IL18 — TCF23

Text-mined interactions from Literome

McDermott et al., Trends Mol Med 2002 (Familial Mediterranean Fever...) : Disorders of interleukin-1 processing and of regulation of nuclear factor kappaB transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Bachmann et al., Mol Cancer Ther 2007 (Leukemia, Myeloid, Acute) : Because T-box expressed in T cells ( T-bet ) is considered to be of paramount importance for dendritic cell function, the effects of IL-18 on this transcription factor have been investigated in the current study
Sheikh et al., Hepatology 2008 (Hepatitis C...) : This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008 (Arthritis, Rheumatoid...) : IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Reddy et al., J Cell Physiol 2011 (Hyperplasia) : In addition to inducing its own expression via phosphatidylinositol 3-kinase/Akt dependent IKK/NF-?B activation, IL-18 stimulated glycogen synthase kinase 3ß phosphorylation and degradation, ß-catenin nuclear translocation and stabilization, T-cell factor-lymphoid enhancer binding factor ( TCF-LEF ) activation, and WISP1 induction
Sung et al., J Biol Chem 1993 : Stimulation of interleukin-1 gene transcription may be caused by the stimulation of transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors