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ANGPT2 — IL1B

Text-mined interactions from Literome

Campese et al., Hypertension 2002 : This raises the possibility that the stimulatory effects of Ang II on central SNS activity may be mediated by inhibition of nNOS and IL-1beta ... Ang II reduced the abundance of IL-1beta and nNOS mRNA in the PH, PVN, and LC ... Pretreatment with losartan ( 10 microg/kg body wt dissolved in 10 microL of aCSF ) given ICV 20 minutes before Ang II abolished the effects of Ang II on BP, RSNA, and NE secretion from the PH and IL-1beta and nNOS mRNA ... In conclusion, these studies suggest that Ang II inhibits the expression of IL-1beta and nNOS in the brain
Shimizu et al., J Pharmacol Exp Ther 2004 (Disease Models, Animal...) : The present study was performed to investigate whether brain ANG II contributes to the fever and IL-1beta production in the rat brain induced by i.c.v. injection of LPS
Xie et al., J Cell Physiol 2004 : DPI almost completely inhibited Ang II + IL-1beta stimulated activation of ERK1/2, while partially inhibiting JNKs. PD98059, ERK1/2 pathway inhibitor, and SP600125, JNKs inhibitor, partially inhibited Ang II + IL-1beta stimulated increases in OPN mRNA
Sasaki et al., Am J Physiol Regul Integr Comp Physiol 2005 (Dehydration...) : We recently reported an involvement of ANG II and the ANG II type 1 (AT1) receptor in the hepatic expression of IL-1beta induced in dehydrated rats by LPS
Kalinski et al., Cancer 2006 (Chondroma...) : As interleukin (IL)-1beta has been found to be an indispensable factor in angiogenic signaling, we further analyzed the effect of IL-1beta on the expression of VEGF-A, Ang-1, and Ang-2 using a previously established cell culture model ... IL-1beta did not activate Ang-2 expression
Sánchez-López et al., American journal of physiology. Renal physiology 2008 : In summary, these data indicate that IL-1beta inhibited ANG II-mediated type IV collagen production, via CTGF downregulation, and increased type IV collagen degradation, through MMP-9 upregulation