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IL1RN — MAPK15

Text-mined interactions from Literome

Zieker et al., Physiol Genomics 2005 : In line with the results of former studies, we observed an upregulation of mitogen activated protein kinase activated protein kinase-2 ( MAPKAP-K2 ), L-selectin, and IL-1 receptor antagonist (IL-1ra) after exhaustive exercise
Zheng et al., Acta Pharmacol Sin 2006 (Arthritis, Experimental) : The increased phosphorylation of MAPK and cell proliferation in fibroblast-like synoviocytes ( FLS ) stimulated by supernatants of MLS in AA rats was also inhibited by IL-1ra ( 10 and 40 mg/kg, ic, d 14-21 )
Sung et al., Acta Anaesthesiol Taiwan 2007 (Hyperalgesia) : I.t. pretreatment of IL-1 receptor antagonist (IL-1ra) , p38 MAPK inhibitor or iNOS inhibitor, inhibits the i.t. IL-1beta induced NO levels and thermal hyperalgesia in rats, likely via either inhibiting the IL-1beta mediated p38 MAPK activation and subsequent iNOS induction, or direct attenuation of the central iNOS activity, which therefore reduces the central sensitization of inflammatory pain