Gene interactions and pathways from curated databases and text-mining

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HLA-DRB1 — IL8

Text-mined interactions from Literome

Choi et al., Mol Cell Biol 2002 (Astrocytoma...) : These findings collectively indicate that DR5 ligation on human glioma cells leads to apoptosis and that the activation of AP-1 and NF-kappaB leads to the induction of IL-8 expression ; these responses are dependent on caspase activation
Tomoda et al., Immunology 1992 (Leukemia, Myeloid) : Among those cytokines, interleukin-1 beta (IL-1 beta) had a positive effect on IFN-gamma dependent induction of MHC class II genes