Gene interactions and pathways from curated databases and text-mining

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JUN — KRT14

Text-mined interactions from Literome

Radoja et al., Mol Cell Biol 2000 (Skin Diseases) : We conclude that GR suppresses keratin gene expression through two independent mechanisms : directly, through interactions of keratin nGREs with four GR monomers, as well as indirectly, by blocking the AP1 induction of keratin gene expression
Wagner et al., Exp Dermatol 2013 (Epidermolysis Bullosa Simplex...) : This observation led us to hypothesize a positive feedback model in which mutant ( R125P ) K14 triggers JNK signalling, leading to increased AP1 dependent expression of K14 , which in turn amplifies JNK signalling further