Gene interactions and pathways from curated databases and text-mining

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LBP — TLR4

Text-mined interactions from Literome

Su et al., Hepatology 2000 : LBP plays an important role in mediating Kupffer cell activation by LPS, and these effects are dependent on the presence of functioning Tlr 4
Lazou Ahrén et al., J Infect Dis 2001 : Lipopolysaccharide binding protein increases toll-like receptor 4-dependent activation by nontypeable Haemophilus influenzae
Coats et al., J Immunol 2005 : Activation of the TLR4 signaling complex requires the coordinated function of LPS binding protein (LBP) , CD14, MD-2, and TLR4
Tsukamoto et al., Int Immunol 2010 : Lipopolysaccharide binding protein mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane associated CD14 expressing cells