Gene interactions and pathways from curated databases and text-mining

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CEBPB — LEP

Text-mined interactions from Literome

Schroeder-Gloeckler et al., J Biol Chem 2007 (Diabetes Mellitus...) : Leptin and the anti-diabetic drug metformin acutely down-regulated C/EBPbeta expression in hepatocytes, whereas fatty acids up-regulate C/EBPbeta expression
Staiger et al., Carcinogenesis 2009 (Adenocarcinoma...) : Thus, C/EBPbeta contributes to endocrine expression of IGF-1, leptin and insulin, which modulate energy balance and can contribute to cancer progression by creating a favorable environment for tumor cell proliferation and survival