Schroeder-Gloeckler et al., J Biol Chem 2007
(Diabetes Mellitus...) :
Leptin and the anti-diabetic drug metformin acutely down-regulated C/EBPbeta expression in hepatocytes, whereas fatty acids up-regulate C/EBPbeta expression
Staiger et al., Carcinogenesis 2009
(Adenocarcinoma...) :
Thus, C/EBPbeta contributes to endocrine expression of IGF-1, leptin and insulin, which modulate energy balance and can contribute to cancer progression by creating a favorable environment for tumor cell proliferation and survival