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FOS — MAP3K8

Text-mined interactions from Literome

Kane et al., Mol Cell Biol 2002 : However, phosphorylation at this site is not required for Cot kinase activity or AP-1 induction , suggesting it specifically regulates Cot effector function at the level of the NF-kappa B pathway
Lee et al., Cancer Res 2009 : Furthermore, inhibition of Tpl2 reduced the arsenite induced promoter activity of NF-kappaB and activator protein-1 (AP-1) , indicating that NF-kappaB and AP-1 are downstream transducers of arsenite triggered Tpl2
Jin et al., Dev Biol 2013 : Second, MAP3K1 potentiated AP-2a expression and SRF and AP-1 activity, but its target genes were enriched for binding motifs of AP-2a and SRF, and not AP-1, suggesting the existence of novel MAP3K1-AP-2a/SRF modules in gene regulation