Gene interactions and pathways from curated databases and text-mining

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MAPK15 — TAC3

Text-mined interactions from Literome

Yamamoto et al., Hypertension 2006 (Cardiac Output, Low...) : On a biochemical level, cardiac angiotensin II concentration and activity of mitogen activated protein ( MAP ) kinases were markedly increased in ACE2 ( -/y ) mice in response to TAC
Vafadari et al., Transplantation 2012 (MAP Kinase Signaling System) : We studied whether TAC inhibits p38 MAPK signaling in primary human T cells and ex vivo in healthy volunteers and kidney transplant recipients ... In vitro, 10-ng/mL TAC inhibited p38 MAPK phosphorylation by a mean of 27 % in CD3, 26 % in CD4, and 34 % in CD8 T cells ( P < 0.01 compared with baseline )