Gene interactions and pathways from curated databases and text-mining

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MAPK8 — SAA1

Text-mined interactions from Literome

Westra et al., Ann Rheum Dis 2006 (Carcinoma, Hepatocellular...) : Production and mRNA expression of CRP and fibrinogen, but not SAA production and mRNA expression, were significantly inhibited by p38 MAPK specific inhibitor in hepatoma cell lines
Lee et al., Exp Mol Med 2009 : LL-37 caused a dramatic inhibition of ERK and p38 MAPK activity, which is induced by SAA
Lee et al., Exp Mol Med 2010 : Inactivation of G ( ( i ) ) protein ( s ) by PTX inhibited the activation of SAA induced ERK, but not p38 MAPK or JNK ... The results indicate that SAA stimulates FPR2 mediated activation of p38 MAPK and JNK, which are independent of a PTX-sensitive G-protein and are essential for SAA induced CCL2 production
Zhai et al., Eur J Pharmacol 2013 : These results indicate that the activation of JNK, p38 mitogen activated protein kinase ( MAPK ) and caspase-3 during apoptosis triggered by MPP ( + ) could be suppressed by SAA ; on the other hand, an MPP ( + ) -induced increase in the expression of Bax in SH-SY5Y cells was blocked by SAA