Cross et al., Blood 2008
:
While TNFalpha had no effect on MCL-1 transcription, it induced expression of another antiapoptotic molecule, BFL-1
Ahmed et al., Arthritis Rheum 2009
(Arthritis, Rheumatoid...) :
In RA synovial fibroblasts, EGCG ( 5-50 microM ) inhibited constitutive and TNFalpha induced Mcl-1 protein expression in a concentration- and time dependent manner ( P < 0.05 )
Cowburn et al., Am J Respir Cell Mol Biol 2011
(Inflammation...) :
We report that granulocyte/macrophage colony stimulating factor ( GM-CSF ) and tumor necrosis factor (TNF)-a prevent the normal time dependent loss of Mcl-1 and Bcl2A1 in neutrophils, and we demonstrate that they cause an NF-?B dependent increase in Bcl-X ( L ) transcription/translation