Gene interactions and pathways from curated databases and text-mining

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MDM2 — TERT

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Gordan et al., Cytotherapy 2002 (Neoplasms) : Four examples of candidate universal tumor Ags reviewed here include the telomerase reverse transcriptase ( hTERT ), the inhibitor of apoptosis survivin, the p53 interacting protein MDM2 , and the cytochrome P450 isoform 1B1 -- each at various levels of preclinical and clinical development
Oh et al., Oncogene 2010 : In this study, we identified posttranslational regulation of human telomerase reverse-transcriptase ( hTERT ) by the E3 ligase Hdm2