Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MED4

Text-mined interactions from Literome

Hoshi et al., J Biol Chem 2000 : The phosphorylation of ERK1/2 was rapidly induced by TRAP and bFGF but not by TNF-alpha
Wang et al., J Biol Chem 2002 : Mediator role of platelet derived growth factor and ERK
Zheng et al., J Neurosci Res 2009 : Surprisingly, BAPTA-AM did not block ERK activation, indicating that [ Ca ( 2+ ) ] ( i ) and Ras-Raf-MAPK are not coupled, and the activation of ERK alone is not sufficient to up-regulate Arc transcription
Panja et al., J Biol Chem 2009 : These results support a dominant role for ERK-MNK signaling in control of translational initiation and Arc synthesis during LTP consolidation in the dentate gyrus
Kumar et al., J Biol Chem 2012 (Synaptic Transmission) : Mechanistically, intracellular mGluR5 mediated Arc induction is dependent upon extracellular and intracellular Ca ( 2+ ) and ERK1/2 as well as calmodulin dependent kinases as known chelators, inhibitors, and a dominant negative Ca ( 2+ ) /calmodulin dependent protein kinase II construct block Arc increases