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CASP6 — MET
Text-mined interactions from Literome
Tulasne et al., Mol Cell Biol 2004
:
We report that stress stimuli induce the
caspase mediated cleavage of
MET in physiological cellular targets, such as epithelial cells, embryonic hepatocytes, and cortical neurons
Huelsenbeck et al., Infect Immun 2007
:
The cytotoxic effect of TcdB was executed by caspase-3, as it was responsive to inhibition by
acetyl-Asp-Met-Gln-Asp-aldehyde ( Ac-DMQD-CHO ), an
inhibitor of
caspase-3
Foveau et al., Cell Death Differ 2007
:
Nonetheless, stress stimuli can lead to a
caspase dependent cleavage of
MET within its juxtamembrane region, which generate a proapoptotic 40 kDa fragment (p40 MET)
McCleese et al., Int J Cancer 2009
(Bone Neoplasms...) :
Finally, STA-1474 induced tumor regression,
caspase-3 activation and downregulation of
p-Met/Met and p-Akt/Akt in OSA xenografts
Barbonetti et al., Endocrinology 2010
:
The
effect of
Met-AEA did not involve activation of
caspase-9 or caspase-3 and was reverted by washing