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MET — SP1

Text-mined interactions from Literome

Zhang et al., American journal of physiology. Renal physiology 2003 : Sp1 and Sp3 transcription factors synergistically regulate HGF receptor gene expression in kidney
Liang et al., Int J Oncol 2004 (Fibrosarcoma) : Sp1 regulates expression of MET , and ribozyme induced down-regulation of MET in fibrosarcoma derived human cells reduces or eliminates their tumorigenicity ... Conversely, inhibition of Sp1 binding to DNA in a fibrosarcoma cell line, using an Sp1 decoy, dramatically reduced MET expression
Verras et al., Cancer Res 2007 (Disease Progression...) : Using different c-Met promoter/reporter constructs, we identified that Sp1 induces the transcription of c-Met and that AR can repress the Sp1 induced transcription in prostate cancer cells
Hwang et al., Proc Natl Acad Sci U S A 2011 (Neoplasm Invasiveness) : Wild-type p53 negatively regulates MET expression by two mechanisms : ( i ) transactivation of MET targeting miR-34, and ( ii ) inhibition of SP1 binding to MET promoter