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MMP10 — SP1
Text-mined interactions from Literome
Mudduluru et al., Biosci Rep 2008
(Colorectal Neoplasms) :
In Drosophila Schneider
SL2-cells , exogenous expression of
Sp1/Sp3 increased Axl promoter activity
Jutooru et al., Mol Pharmacol 2010
(Pancreatic Neoplasms) :
CDDO-Me also induced reactive oxygen species ( ROS ) and decreased mitochondrial membrane potential ( MMP ) in Panc1 and L3.6pL cells, and cotreatment with antioxidants ( glutathione and dithiothreitol ) blocked the formation of ROS, reversed the loss of
MMP , and
inhibited down-regulation of
Sp1 , Sp3, and Sp4