Gene interactions and pathways from curated databases and text-mining

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MMP14 — MMP15

Text-mined interactions from Literome

Ellerbroek et al., Cancer Res 1999 (Ovarian Neoplasms) : Aggregation of beta1 integrins with immobilized 21C8 or P4C10 antibodies stimulated MMP dependent pro-MMP-2 activation and accumulation of a M ( r ) 43,000 form of membrane type 1 MMP (MT1-MMP) , a cell surface activator of pro-MMP-2, in cell extracts
Majka et al., Invest Ophthalmol Vis Sci 2001 (Disease Models, Animal...) : During the angiogenic period from P13 to P17, MMP-2 and -9, and MT1-MMP message expression increased in experimental retinas compared with control samples
Ruangpanit et al., Exp Cell Res 2002 : Accumulation of collagen over time correlated with increased levels of both mature MMP-2 and cell associated membrane type 1-MMP (MT1-MMP) , and subsequently increased mRNA levels for MT1-MMP , providing temporal resolution of the `` nontranscriptional '' and `` transcriptional '' effects of collagen on MT-1MMP functionality
Munshi et al., J Biol Chem 2004 (Carcinoma, Squamous Cell...) : Treatment of oral squamous cell carcinoma cells with TGF-beta1 promoted MMP dependent cell scattering and collagen invasion, increased expression of MMP-2 and MT1-MMP , and enhanced MMP-2 activation
Sanka et al., Invest Ophthalmol Vis Sci 2007 : Primary human TM ( HTM ) cells treated with different actin cytoskeleton interfering agents, including cytochalasin D, latrunculin A, ethacrynic acid ( ECA ), a Rho kinase inhibitor ( Y-27632 ), and H-7 ( serine/threonine kinase inhibitor ), were examined for changes in actin cytoskeletal organization by phalloidin staining, MMP-2 activation by gelatin zymography, expression of MT1-MMP by quantitative real-time PCR analysis, levels of tissue inhibitor of metalloproteinases ( TIMP-1 and TIMP-2 ), and activation of p38 mitogen activated protein kinase ( p38 MAPK ) and extracellular signal regulated protein kinase ( ERK ) by immunoblotting
Ito et al., Biochem Biophys Res Commun 2010 (Disease Progression...) : In HT1080 cells, positive both in MT1-MMP and MT2-MMP , the migration as well as the invasion was impaired by MT1-MMP or MT2-MMP suppression ... In HT1080 cells, positive both in MT1-MMP and MT2-MMP , the migration as well as the invasion was impaired by MT1-MMP or MT2-MMP suppression
Swamydas et al., Cell Adh Migr 2013 (Mammary Neoplasms, Animal...) : Additionally, the addition of specific MMP9/MMP13 and MMP14 inhibitors prevented the MMP activities of supernatants collected from 4T1 cells incubated with D1CM, CCL5 or CCL9