Gene interactions and pathways from curated databases and text-mining

◀ Back to MMP1

MMP1 — MMP15

Text-mined interactions from Literome

Yokoyama et al., Aliment Pharmacol Ther 2000 (Helicobacter Infections...) : Whereas MMP-1 was not detected in media from fibroblasts or H. pylori culture alone, MMP-1 was detected in cocultures ( P < 0.01 )
Sundstrom et al., AIDS Res Hum Retroviruses 2001 (Cardiomyopathies...) : Low levels of constitutively expressed MMP-1 and -2 were detected in individual cultures of HMVEC-C and PBMCs. NE did not induce MMP or TIMP expression by HMVEC-C and caused modest increases ( 3- to 4-fold ) in MMP-1 and -2 by uninfected PBMCs. Increased levels of NE-induced MMP-1 ( 5-fold ) and MMP -2 ( 15-fold ) were detected in cocultures of HMVEC-C and uninfected PBMCs. HIV infection enhanced MMP-1 ( 46-fold ) and MMP-2 ( 48-fold ) and active MMP-7 ( 33-fold ) and MMP-9 ( 50-fold ) by PBMCs. Coculture of HIV infected PBMCs with HMVEC-C increased MMP-1 ( 110-fold ) and MMP-2 ( 307-fold ) but not active MMP-7 and -9
Suzuki et al., Exp Toxicol Pathol 2001 (Fibrosis) : In conclusion, these findings suggest that the activity of MMPs may bealtered by MMP-1 downregulation and inhibition of MMP activity by PAl-1 and TIMP-1 generated from tubular epithelial cells
Bogatkevich et al., Arthritis Rheum 2007 (MAP Kinase Signaling System...) : Inhibition of MMP activity by MMP inhibitor GM1489 and inhibition of MMP-1 expression by siRNA did not prevent HGF induced ERK-1/2 phosphorylation and NF-kappaB activity, but significantly restored HGF inhibited collagen and CTGF accumulation
La et al., J Periodontol 2009 : Grape seed extract suppresses lipopolysaccharide induced matrix metalloproteinase ( MMP ) secretion by macrophages and inhibits human MMP-1 and -9 activities
Ito et al., Biochem Biophys Res Commun 2010 (Disease Progression...) : In HT1080 cells, positive both in MT1-MMP and MT2-MMP , the migration as well as the invasion was impaired by MT1-MMP or MT2-MMP suppression
Wang et al., Gynecol Oncol 2011 (Neoplasm Invasiveness...) : Furthermore, MMP-1 and PAR1 were both significantly induced by LPA ( 20 µM ), and siRNA silencing of MMP-1 and PAR1 both significantly reduced LPA 's invasion promoting effect in DOV13 cells ( p < 0.05 )