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Das et al., Life Sci 2008
(Breast Neoplasms) :
Blocking of alpha5beta 1 integrin with anti-alpha5 monoclonal antibody inhibits the fibronectin induced MMP activation response appreciably
Huhtala et al., J Cell Biol 1995
:
In contrast, peptide V from the heparin binding region, shown previously to stimulate focal contact formation, further enhanced MMP expression by RSF when present on the substrate with 120FN. RSF expressed alpha 4 beta 1 integrin , the receptor for CS-1, and the anti-alpha 4 mAb blocked the ability of CS-1 to suppress MMP induction by 120FN