Gene interactions and pathways from curated databases and text-mining

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IL10 — MMP27

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
John et al., Exp Lung Res 2002 (Pneumonia, Bacterial...) : The endogenous production of IL-10 in AM of patients with sarcoidosis and the MMP downregulation by exogenous IL-10 suggest an involvement of IL-10 in MMP regulation
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Perianayagam et al., Eur J Clin Invest 2005 (Uremia) : We hypothesized that previously reported defective synthesis of IL-10 by immunocompetent cells exposed to a uraemic milieu may be due to impaired mitochondrial membrane potential ( MMP )
Hu et al., Zhonghua Xin Xue Guan Bing Za Zhi 2008 (Myocardial Infarction...) : In vivo myocardial IL-10 transfer reduced myocardial MMP and collagen expression and increasing the TIMP expression
Coussens et al., Immunology 2009 (Tuberculosis) : We therefore determined the effects of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on expression, secretion and activity of a number of MMP and TIMP in M. tuberculosis infected human leucocytes ; we also investigated the effect of 1alpha,25 ( OH ) ( 2 ) D ( 3 ) on the secretion of interleukin-10 (IL-10) and prostaglandin E ( 2 ) ( PGE ( 2 ) ), both transcriptional regulators of MMP expression
Stearns et al., Invasion Metastasis 1997 (Bone Neoplasms...) : However IL-10 may inhibit the production of matrix metalloproteases ( MMP ) and prevent the establishment of metastasis
Wagner et al., J Neurooncol 1998 (Brain Neoplasms...) : In all but one cell line no enhancement of MMP expression by IL-10 was detected