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MMP9 — SOD2

Text-mined interactions from Literome

Nelson et al., Clin Cancer Res 2003 (MAP Kinase Signaling System...) : The Sod2 dependent increases in AP-1 and SP-1 DNA binding activity, MMP-1 promoter activity, general MMP expression, and collagen degradation can be reversed by the hydrogen peroxide detoxifying enzyme, catalase
Shin et al., Free Radic Biol Med 2008 : On the other hand, SOD inhibited heat shock induced activity of MMP-9 induction, but not MMP-1
Bernard et al., Inflammation 2008 (Atherosclerosis...) : SOD and catalase increased MMP9 expression, protein level and activity of not equal HL60, but migration of not equal HL60 cells was only decreased by catalase, demonstrating that ROS are more efficient in modulating MMP9 activity of not equal HL60 than their mobility
Liu et al., Mol Cell Biochem 2009 (Liver Cirrhosis...) : Heparin-SOD could markedly attenuate the mRNA expression of TGF-beta1, MMP-2 , and collagen-I
Song et al., BMB Rep 2011 : In this study, we examined the effect of a cell-permeable superoxide dismutase ( Tat-SOD ) on TNF-a induced MMP-9 expression in human keratinocyte cells ( HaCaT ) ... In addition, Tat-SOD suppressed TNF-a induced gelatinolytic activity of MMP-9 ... Taken together, our results indicate that Tat-SOD can suppress TNF-a induced MMP-9 expression via ROS-NF-?B dependent mechanisms in keratinocytes, and therefore can be used as an immunomodulatory agent against inflammatory skin diseases related to oxidative stress