Lee et al., Am J Physiol Lung Cell Mol Physiol 2006
(Carcinoma, Mucoepidermoid...) :
PPAR-gamma agonists or specific inhibitors of phosphoinositide 3-kinase exert inhibition of cigarette smoke induced mucin production, with the upregulation of PTEN signaling and downregulation of Akt expression
Kim et al., Biochem Biophys Res Commun 2012
:
HMGB1 activated the JNK and PI3K/Akt signaling pathways, and inhibitors of JNK and PI3K/Akt markedly inhibited HMGB1 induced MUC8 expression