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MYL12B — RHO
Text-mined interactions from Literome
Zhou et al., Am J Physiol Cell Physiol 2004
:
In contrast, sustained contraction and
MLC(20) phosphorylation were partially
inhibited by a PKC or
Rho kinase inhibitor ( bisindolylmaleimide and Y-27632 ) and abolished by a combination of both inhibitors but not affected by U-73122 or ML-9
Obara et al., J Vasc Res 2005
(Disease Models, Animal...) :
The development of cerebral vasospasm after SAH ( on day 4 ) is caused by at least two mechanisms : one involves
MLC20 phosphorylation mediated by the inhibition of MLC20 phosphatase by Rho-kinase, and the other CaD phosphorylation
mediated by the activation of PKC-delta by
Rho-kinase , which results in the alleviation of the inhibition by CaD of myosin Mg2+-ATPase activity
Wang et al., PloS one 2012
:
Furthermore, Y27632, a specific inhibitor of
Rho kinase (ROK) , notably
suppressed Tg-stimulated myometrial contractions and decreased
MLC20 phosphorylation