Gene interactions and pathways from curated databases and text-mining

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MYLIP — PDLIM7

Text-mined interactions from Literome

Motsch et al., RNA Biol 2007 (Burkitt Lymphoma) : Epstein-Barr virus encoded latent membrane protein 1 (LMP1) induces the expression of the cellular microRNA miR-146a ... We show that the EBV encoded latent membrane protein 1 (LMP1) induces the expression of miR-146a via NFkappaB ... LMP1 activates the miR-146a promoter but not a promoter with a mutation of the NFkappaB-response elements
Gatto et al., Nucleic Acids Res 2008 : LMP1 , but not LMP2, up-regulated the expression of miR-155 , when transfected in EBV negative B cells ... The induction of p65 binding together with increased RNA polymerase II binding, confirms that LMP1 mediated activation of miR-155 occurs transcriptionally ... Finally, we demonstrate that LMP1 mediated activation of miR-155 in an EBV negative background correlates with reduction of protein PU.1, which is a possible miR target
Yu et al., J Virol 2012 (Epstein-Barr Virus Infections) : EBV-LMP1 mediated the downregulation of miR-203 at the primary transcript level
Forte et al., J Virol 2012 (Epstein-Barr Virus Infections) : EBV latent membrane protein 1 (LMP1) was sufficient to induce miR-34a requiring downstream NF-?B activation but independent of functional p53