Gene interactions and pathways from curated databases and text-mining

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NA — SOD1

Text-mined interactions from Literome

Yagci et al., J Gastroenterol 2004 (Acute Disease...) : NAC had no effect on pancreatic superoxide dismutase level
Chen et al., Acta Pharmacol Sin 2005 (MPTP Poisoning) : Rg1 or NAC prevented GSH reduction and T-SOD activation in substantia nigra, and attenuated the phosphorylations of JNK and c-Jun following MPTP treatment
Duru et al., Ren Fail 2008 (Acute Kidney Injury...) : Moreover, NAC significantly reduced MAD and NO levels and increased SOD and GSH-Px activities in serum and renal tissue, as well as provided a histologically proven protection against CsA induced nephrotoxicity
Lu et al., J Clin Neurosci 2009 (Brain Edema...) : We further investigated the mechanism involved in the neuroprotective effects of NAC on rat brain tissue and found that NAC significantly increased CuZn-SOD and GSH-Px activity and decreased MDA content in the SAH brain
Ozyilmaz et al., Intensive Care Med 2011 (Kidney Diseases) : NAC exhibited no significant effect on biochemical parameters but reduced renal tissue SOD level and reversed immunocytochemical staining of inducible nitric oxide synthase (i-NOS) and neurotrophin-3
Kim et al., Chemosphere 2013 : NAC reduced SOD activity and intracellular GSH level in yeast
van Klaveren et al., Exp Lung Res 1997 (Hyperoxia) : After 85 % O2 U-74389G increased gamma-GT, SOD, and GSH by +72, +58, and +68 %, respectively, while NAC only increased SOD ( +49 % ) and GSH ( +26 % ) compared to the oxygen exposed cells not treated with NAC or U-74389G