Gene interactions and pathways from curated databases and text-mining

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CNR1 — NEUROD4

Text-mined interactions from Literome

Watson et al., Mol Cell Neurosci 2008 : In this study, we show that the CB1 receptor has a wide expression pattern in the developing nervous system and that its expression follows neuronal differentiation in the embryo from the earliest stages
Bromberg et al., Science 2008 : Cannabinoid receptor 1 ( CB1R ) regulates neuronal differentiation
Compagnucci et al., PloS one 2013 : Type-1 ( CB1 ) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells
Xapelli et al., PloS one 2013 : Here, we describe the effect of type 1 cannabinoid receptor ( CB1R ) activation on self-renewal, proliferation and neuronal differentiation in mouse neonatal subventricular zone ( SVZ ) stem/progenitor cell cultures ... Surprisingly, stimulation of CB1R by R-m-AEA also promoted neuronal differentiation ( without affecting glial differentiation ), at 7 days, as shown by counting the number of NeuN positive neurons in the cultures ... Taken together, these results demonstrate that CB1R activation induces proliferation, self-renewal and neuronal differentiation from mouse neonatal SVZ cell cultures