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IFNG — NEUROD4

Text-mined interactions from Literome

Wong et al., Exp Neurol 2004 : Interferon-gamma but not TNF alpha promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells ... Under differentiating conditions, neither cytokine was toxic ; however, IFN gamma enhanced neuronal differentiation , rapidly increasing beta III-tubulin positive cell numbers 3-4 fold and inhibiting astrocyte generation
Song et al., J Biol Chem 2005 : Here we studied the underlying mechanism for IFN-gamma induced neuronal differentiation using the human neuroblastoma Paju cell line
Zahir et al., Stem Cells Dev 2009 : These in vitro screens showed that of all the different treatments, dibutyryl cyclic AMP ( dbcAMP ) and interferon-gamma (IFN-gamma) enhanced neuronal differentiation most significantly compared to the 1 % fetal bovine serum ( FBS ) controls
Arien-Zakay et al., Leukemia 2009 (Neuroblastoma) : Interferon-gamma induced neuronal differentiation of human umbilical cord blood derived progenitors ... These data indicate that IFN-gamma promotes neuronal differentiation of HUCB derived progenitors, proposing its use in future protocols towards cell therapy