◀ Back to CD28

CD28 — NFKBIA

Text-mined interactions from Literome

Pioli et al., Eur J Immunol 1999 : Cytotoxic T lymphocyte antigen 4 ( CTLA-4 ) inhibits CD28 induced IkappaBalpha degradation and RelA activation
Li et al., J Biol Chem 2005 : Finally, we found that TCR/CD28 costimulation induces IkappaBalpha , IkappaBbeta, and IkappaBepsilon degradation, and PKC is required for IkappaBalpha and IkappaBepsilon but not IkappaBbeta degradation
Lai et al., J Biol Chem 1994 : CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin ... We showed that CD28 signaling, distinct from other stimuli such as phorbol 12-myristate 13-acetate, IL-1, and tumor necrosis factor-alpha, caused a sustained down-regulation of the inhibitor I kappa B alpha in Jurkat T cells ... Remarkably, the CD28 mediated down-regulation of I kappa B alpha was prevented by rapamycin but not by CsA
Harhaj et al., J Biol Chem 1998 : Catalytically inactive forms of IKKs are able to block the in vivo phosphorylation of IkappaB alpha induced by mitogen and CD28