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NFKBIA — VEGFA
Text-mined interactions from Literome
Kiriakidis et al., J Cell Sci 2003
(Inflammation...) :
VEGF expression in human macrophages is NF-kappaB
dependent : studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the
IkappaB kinase 2
Xu et al., Oncogene 2005
(Prostatic Neoplasms) :
Analogous to treatments with SFN and PEITC,
SR-IkappaBalpha also strongly
inhibited NF-kappaB transcriptional activity as well as
VEGF , cylcin D1, and Bcl-X ( L ) expression
Tong et al., Respir Res 2006
:
In addition, HIMF strongly induced Akt phosphorylation, and suppression of Akt activation by specific inhibitors and dominant negative mutants for PI-3K, and IKK or
IkappaBalpha blocked HIMF induced NF-kappaB activation and
attenuated HIMF induced
VEGF production